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I-BRD9

I-BRD9

Catalog Number: CC7991 Rank: comment rank 5

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Description:

I-BRD9 (GSK602) is a potent and selective BRD9 inhibitor with pIC50 of 7.3, while it displayed a pIC50 of 5.3 against BRD4.

Chemical Information:

Molecular Weight (MW) 497.55
Formula

 

C22H22F3N3O3S2

 

CAS No. 1714146-59-4
Solubility (25°C) * DMSO 99 mg/mL (198.97 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
GSK3α GSK3β
6.9 nM 31 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0098 mL 10.0492 mL 20.0985 mL
5 mM 0.4020 mL 2.0098 mL 4.0197 mL
10 mM 0.2010 mL 1.0049 mL 2.0098 mL
50 mM 0.0402 mL 0.2010 mL 0.4020 mL


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