Description：

I-BET-762 is an inhibitor for BET proteins with IC50 of ~35 nM in a cell-free assay, suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation, highly selective over other bromodomain-containing proteins.

Chemical Information：

Molecular Weight (MW)		423.9
Formula		C22H22ClN5O2
CAS No.		1260907-17-2
Solubility (25°C) *	DMSO	84 mg/mL (198.15 mM)
	Water	Insoluble
	Alcohol	42 mg/mL warmed (99.07 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3590 mL	11.7952 mL	23.5905 mL
5 mM	0.4718 mL	2.3590 mL	4.7181 mL
10 mM	0.2359 mL	1.1795 mL	2.3590 mL
50 mM	0.0472 mL	0.2359 mL	0.4718 mL

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