Description：

NVP-HSP990 (HSP990) is a novel, potent and selective HSP90 inhibitor for HSP90α/β with IC50 of 0.6 nM/0.8 nM.

Chemical Information：

Molecular Weight (MW)		379.39
Formula		C20H18FN5O2
CAS No.		934343-74-5
Solubility (25°C) *	DMSO	75 mg/mL (197.68 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

CDK2 DNAPK ATR CDK1 1.3 μM (Ki) 2.2 μM (Ki) 0.4 μM (Ki) 2.5 μM (Ki)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6358 mL	13.1791 mL	26.3581 mL
5 mM	0.5272 mL	2.6358 mL	5.2716 mL
10 mM	0.2636 mL	1.3179 mL	2.6358 mL
50 mM	0.0527 mL	0.2636 mL	0.5272 mL

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