Description：

HO-3867, an analog of curcumin, is a selective STAT3 inhibitor that inhibits its phosphorylation, transcription, and DNA binding without affecting the expression of other active STATs.

Chemical Information：

Molecular Weight (MW)		464.55
Formula		C28H30F2N2O2
CAS No.		1172133-28-6
Solubility (25°C) *	DMSO	13 mg/mL warmed (27.98 mM)
	Water	Insoluble
	Alcohol	6 mg/mL warmed (12.91 mM)

Biological Activity：

Targets IC50

ERK2 ERK1 1 nM 4 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1526 mL	10.7631 mL	21.5262 mL
5 mM	0.4305 mL	2.1526 mL	4.3052 mL
10 mM	0.2153 mL	1.0763 mL	2.1526 mL
50 mM	0.0431 mL	0.2153 mL	0.4305 mL

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