Description：

Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator with EC50 of 4.61 ± 1.29 μM; It can also attenuate Wnt/beta-catenin signaling through the Siah-1-mediated beta-catenin degradation.

Chemical Information：

Molecular Weight (MW)		406.90
Formula		C13H6Cl6O2
CAS No.		70-30-4
Solubility (25°C) *	DMSO	81 mg/mL (199.06 mM)
	Water	Insoluble
	Alcohol	81 mg/mL (199.06 mM)

Biological Activity：

Targets IC50

Wnt 180 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4576 mL	12.2880 mL	24.5761 mL
5 mM	0.4915 mL	2.4576 mL	4.9152 mL
10 mM	0.2458 mL	1.2288 mL	2.4576 mL
50 mM	0.0492 mL	0.2458 mL	0.4915 mL

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