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Description:
HA15 is a molecule that targets specifically BiP/GRP78/HSPA5. HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
Chemical Information:
Molecular Weight (MW) 466.58 Formula
C23H22N4O3S2
CAS No. 1609402-14-3 Solubility (25°C) * DMSO 93 mg/mL (199.32 mM) Water Insoluble Alcohol 45 mg/mL (96.44 mM)
Biological Activity:
Targets IC50
Kit Lck Fyn Bcr-Abl ~75 nM 5 nM 6 nM 1 μM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.1433 mL 10.7163 mL 21.4326 mL 5 mM 0.4287 mL 2.1433 mL 4.2865 mL 10 mM 0.2143 mL 1.0716 mL 2.1433 mL 50 mM 0.0429 mL 0.2143 mL 0.4287 mL
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