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HA15

HA15

Catalog Number: CC8455 Rank: comment rank 5

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Description:

HA15 is a molecule that targets specifically BiP/GRP78/HSPA5. HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.

Chemical Information:

Molecular Weight (MW) 466.58
Formula

 

C23H22N4O3S2

 

CAS No. 1609402-14-3
Solubility (25°C) * DMSO 93 mg/mL (199.32 mM)
Water Insoluble
Alcohol 45 mg/mL (96.44 mM)


Biological Activity:

Targets
IC50
Kit Lck Fyn Bcr-Abl
~75 nM 5 nM 6 nM 1 μM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.1433 mL 10.7163 mL 21.4326 mL
5 mM 0.4287 mL 2.1433 mL 4.2865 mL
10 mM 0.2143 mL 1.0716 mL 2.1433 mL
50 mM 0.0429 mL 0.2143 mL 0.4287 mL


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