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Endocrinology & Hormones >
Estrogen/progestogen Receptor modulator >
4-Hydroxytamoxifen
Description:
4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer.
Chemical Information:
Molecular Weight (MW) 387.51 Formula
C26H29NO2
CAS No. 68392-35-8 Solubility (25°C) * DMSO 77 mg/mL (198.7 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
EGFR 0.70 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.5806 mL 12.9029 mL 25.8058 mL 5 mM 0.5161 mL 2.5806 mL 5.1612 mL 10 mM 0.2581 mL 1.2903 mL 2.5806 mL 50 mM 0.0516 mL 0.2581 mL 0.5161 mL
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