Description：

(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with K_i of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4.

Chemical Information：

Molecular Weight (MW)		242.32
Formula		C15H18N2O
CAS No.		102518-79-6
Solubility (25°C) *	DMSO	0.66 mg/mL (2.72 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

mTORC1 mTOR mTORC2 8 nM 9.9 nM 166 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	4.1268 mL	20.6339 mL	41.2677 mL
5 mM	0.8254 mL	4.1268 mL	8.2535 mL
10 mM	0.4127 mL	2.0634 mL	4.1268 mL
50 mM	0.0825 mL	0.4127 mL	0.8254 mL

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