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GZD824 Dimesylate

GZD824 Dimesylate

Catalog Number: CC7350 Rank: comment rank 5

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$ 118.00
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Description:

GZD824 Dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.

Chemical Information:

Molecular Weight (MW) 724.77
Formula

 

C29H27F3N6O.2CH4O3S

 

CAS No. 1421783-64-3
Solubility (25°C) * DMSO 100 mg/mL (137.97 mM)
Water 100 mg/mL (137.97 mM)
Alcohol Insoluble


Biological Activity:

Targets
IC50
DOT1L
0.4 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.3797 mL 6.8987 mL 13.7975 mL
5 mM 0.2759 mL 1.3797 mL 2.7595 mL
10 mM 0.1380 mL 0.6899 mL 1.3797 mL
50 mM 0.0276 mL 0.1380 mL 0.2759 mL


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