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Description:
GZD824 Dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.
Chemical Information:
Molecular Weight (MW) 724.77 Formula
C29H27F3N6O.2CH4O3S
CAS No. 1421783-64-3 Solubility (25°C) * DMSO 100 mg/mL (137.97 mM) Water 100 mg/mL (137.97 mM) Alcohol Insoluble
Biological Activity:
Targets IC50
DOT1L 0.4 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.3797 mL 6.8987 mL 13.7975 mL 5 mM 0.2759 mL 1.3797 mL 2.7595 mL 10 mM 0.1380 mL 0.6899 mL 1.3797 mL 50 mM 0.0276 mL 0.1380 mL 0.2759 mL
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