Description：

GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted.

Chemical Information：

Molecular Weight (MW)		520.94
Formula		C15H8Br2INO2
CAS No.		220904-83-6
Solubility (25°C) *	DMSO	104 mg/mL (199.63 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Caspase

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9196 mL	9.5980 mL	19.1961 mL
5 mM	0.3839 mL	1.9196 mL	3.8392 mL
10 mM	0.1920 mL	0.9598 mL	1.9196 mL
50 mM	0.0384 mL	0.1920 mL	0.3839 mL

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