Description：

GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2.

Chemical Information：

Molecular Weight (MW)		275.3
Formula		C17H13N3O
CAS No.		504433-23-2
Solubility (25°C) *	DMSO	25 mg/mL (90.81 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

PI3Kβ PI3Kγ PI3Kδ 1.1 μM 27 nM 8.2 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.6324 mL	18.1620 mL	36.3240 mL
5 mM	0.7265 mL	3.6324 mL	7.2648 mL
10 mM	0.3632 mL	1.8162 mL	3.6324 mL
50 mM	0.0726 mL	0.3632 mL	0.7265 mL

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