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GW0742

GW0742

Catalog Number: CC8176 Rank: comment rank 5

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Description:

GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ.

Chemical Information:

Molecular Weight (MW) 471.49
Formula

 

C21H17F4NO3S2

 

CAS No. 317318-84-6
Solubility (25°C) * DMSO 94 mg/mL (199.36 mM)
Water Insoluble
Alcohol 44 mg/mL (93.32 mM)


Biological Activity:

Targets
IC50
ML-IAP-BIR3 cIAP1-BIR3 cIAP2-BIR3 XIAP-BIR3
14 nM (Ki) 17 nM (Ki) 43 nM (Ki) 28 nM (Ki)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.1209 mL 10.6047 mL 21.2094 mL
5 mM 0.4242 mL 2.1209 mL 4.2419 mL
10 mM 0.2121 mL 1.0605 mL 2.1209 mL
50 mM 0.0424 mL 0.2121 mL 0.4242 mL


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