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Description:
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.
Chemical Information:
Molecular Weight (MW) 385.4 Formula
C21H16FN7
CAS No. 1608125-21-8 Solubility (25°C) * DMSO 77 mg/mL (199.79 mM) Water Insoluble Alcohol 77 mg/mL (199.79 mM)
Biological Activity:
Targets IC50
Aurora A Aurora B Aurora C 9 nM 31 nM 3.4 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.5947 mL 12.9735 mL 25.9471 mL 5 mM 0.5189 mL 2.5947 mL 5.1894 mL 10 mM 0.2595 mL 1.2974 mL 2.5947 mL 50 mM 0.0519 mL 0.2595 mL 0.5189 mL
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