Description：

GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.

Chemical Information：

Molecular Weight (MW)		425.48
Formula		C21H27N7O3
CAS No.		937174-76-0
Solubility (25°C) *	DMSO	39 mg/mL (91.66 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Nonsense mutatio ~0.1 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3503 mL	11.7514 mL	23.5029 mL
5 mM	0.4701 mL	2.3503 mL	4.7006 mL
10 mM	0.2350 mL	1.1751 mL	2.3503 mL
50 mM	0.0470 mL	0.2350 mL	0.4701 mL

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