Description：

GSK461364 inhibits purified Plk1 with K_i of 2.2 nM in a cell-free assay. It is more than 1000-fold selective against Plk2/3. Phase 1.

Chemical Information：

Molecular Weight (MW)		543.6
Formula		C27H28F3N5O2S
CAS No.		929095-18-1
Solubility (25°C) *	DMSO	10 mg/mL (18.39 mM)
	Water	Insoluble
	Alcohol	30 mg/mL (55.18 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8396 mL	9.1979 mL	18.3959 mL
5 mM	0.3679 mL	1.8396 mL	3.6792 mL
10 mM	0.1840 mL	0.9198 mL	1.8396 mL
50 mM	0.0368 mL	0.1840 mL	0.3679 mL

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