Description：

GSK2334470 is a novel PDK1 inhibitor with IC50 of ~10 nM in a cell-free assay, with no activity at other close related AGC-kinases.

Chemical Information：

Molecular Weight (MW)		462.59
Formula		C25H34N8O
CAS No.		1227911-45-6
Solubility (25°C) *	DMSO	90 mg/mL (194.55 mM)
	Water	Insoluble
	Alcohol	90 mg/mL (194.55 mM)

Biological Activity：

Targets IC50

JNK1 JNK3 JNK2 4.7 nM 1 nM 18.7 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1617 mL	10.8087 mL	21.6174 mL
5 mM	0.4323 mL	2.1617 mL	4.3235 mL
10 mM	0.2162 mL	1.0809 mL	2.1617 mL
50 mM	0.0432 mL	0.2162 mL	0.4323 mL

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