Description：

GSK1838705A is a potent IGF-1R inhibitor with IC50 of 2.0 nM, modestly potent to IR and ALK with IC50 of 1.6 nM and 0.5 nM, respectively, and little activity to other protein kinases.

Chemical Information：

Molecular Weight (MW)		532.57
Formula		C27H29FN8O3
CAS No.		1116235-97-2
Solubility (25°C) *	DMSO	107 mg/mL (200.91 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8777 mL	9.3884 mL	18.7769 mL
5 mM	0.3755 mL	1.8777 mL	3.7554 mL
10 mM	0.1878 mL	0.9388 mL	1.8777 mL
50 mM	0.0376 mL	0.1878 mL	0.3755 mL

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