Description：

GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.

Chemical Information：

Molecular Weight (MW)		507.63
Formula		C30H33N7O
CAS No.		942918-07-2
Solubility (25°C) *	DMSO	93 mg/mL (183.2 mM)
	Water	Insoluble
	Alcohol	8 mg/mL (15.75 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9699 mL	9.8497 mL	19.6994 mL
5 mM	0.3940 mL	1.9699 mL	3.9399 mL
10 mM	0.1970 mL	0.9850 mL	1.9699 mL
50 mM	0.0394 mL	0.1970 mL	0.3940 mL

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