Description：

GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.

Chemical Information：

Molecular Weight (MW)		389.45
Formula		C22H23N5O2
CAS No.		1373422-53-7
Solubility (25°C) *	DMSO	77 mg/mL (197.71 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5677 mL	12.8386 mL	25.6772 mL
5 mM	0.5135 mL	2.5677 mL	5.1354 mL
10 mM	0.2568 mL	1.2839 mL	2.5677 mL
50 mM	0.0514 mL	0.2568 mL	0.5135 mL

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