Description：

AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.

Chemical Information：

Molecular Weight (MW)		471.55
Formula		C26H29N7O2
CAS No.		1401033-86-0
Solubility (25°C) *	DMSO	0.01 mg/mL (0.02 mM)
	Water	Insoluble
	Alcohol

Biological Activity：

Targets IC50

Microtubules

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1207 mL	10.6033 mL	21.2067 mL
5 mM	0.4241 mL	2.1207 mL	4.2413 mL
10 mM	0.2121 mL	1.0603 mL	2.1207 mL
50 mM	0.0424 mL	0.2121 mL	0.4241 mL

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