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Description:
Golvatinib (E7050) is a dual c-Met and VEGFR-2 inhibitor with IC50 of 14 nM and 16 nM, does not inhibit bFGF-stimulated HUVEC growth (up to 1000 nM). Phase 1/2.
Chemical Information:
Molecular Weight (MW) 633.69 Formula
C33H37F2N7O4
CAS No. 928037-13-2 Solubility (25°C) * DMSO 20 mg/mL (31.56 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.5781 mL 7.8903 mL 15.7806 mL 5 mM 0.3156 mL 1.5781 mL 3.1561 mL 10 mM 0.1578 mL 0.7890 mL 1.5781 mL 50 mM 0.0316 mL 0.1578 mL 0.3156 mL
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