Description：

GNE-7915 is a highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor, with IC50 and K_i of 9 nM and 1 nM, respectively.

Chemical Information：

Molecular Weight (MW)		443.40
Formula		C19H21F4N5O3
CAS No.		1351761-44-8
Solubility (25°C) *	DMSO	22 mg/mL warmed (49.61 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2553 mL	11.2765 mL	22.5530 mL
5 mM	0.4511 mL	2.2553 mL	4.5106 mL
10 mM	0.2255 mL	1.1276 mL	2.2553 mL
50 mM	0.0451 mL	0.2255 mL	0.4511 mL

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