Description：

AMG 337 is an oral, small molecule, ATP-competitive, highly selective inhibitor of the MET receptor.

Chemical Information：

Molecular Weight (MW)		463.46
Formula		C23H22FN7O3
CAS No.		1173699-31-4
Solubility (25°C) *	DMSO	95 mg/mL (204.97 mM)
	Water	Insoluble
	Alcohol	95 mg/mL (204.97 mM)

Biological Activity：

Targets IC50

Aurora B 0.37 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1577 mL	10.7884 mL	21.5768 mL
5 mM	0.4315 mL	2.1577 mL	4.3154 mL
10 mM	0.2158 mL	1.0788 mL	2.1577 mL
50 mM	0.0432 mL	0.2158 mL	0.4315 mL

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