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Glycyrrhizin (Glycyrrhizic Acid)

Glycyrrhizin (Glycyrrhizic Acid)

Catalog Number: CC2458 Rank: comment rank 5

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Description:

Glycyrrhizin (Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress; modulates P38 and P-JNK but not p-ERK signalling; Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO).

Chemical Information:

Molecular Weight (MW) 822.93
Formula

 

C42H62O16

 

CAS No. 1405-86-3
Solubility (25°C) * DMSO 100 mg/mL (121.51 mM)
Water Insoluble
Alcohol 100 mg/mL (121.51 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.2152 mL 6.0759 mL 12.1517 mL
5 mM 0.2430 mL 1.2152 mL 2.4303 mL
10 mM 0.1215 mL 0.6076 mL 1.2152 mL
50 mM 0.0243 mL 0.1215 mL 0.2430 mL


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