Description：

GLPG0634 analogue is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.

Chemical Information：

Molecular Weight (MW)		410.43
Formula		C23H18N6O2
CAS No.		1206101-20-3
Solubility (25°C) *	DMSO	0.1 mg/mL (0.24 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4365 mL	12.1823 mL	24.3647 mL
5 mM	0.4873 mL	2.4365 mL	4.8729 mL
10 mM	0.2436 mL	1.2182 mL	2.4365 mL
50 mM	0.0487 mL	0.2436 mL	0.4873 mL

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