Description：

GKT137831 is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectivelyl; ~10-fold selectivity towards NOX1, 4 and 5 over NOX2, does not inhibit XO or scavange ROS/RNS.

Chemical Information：

Molecular Weight (MW)		394.85
Formula		C21H19ClN4O2
CAS No.		1218942-37-0
Solubility (25°C) *	DMSO	78 mg/mL warmed (197.54 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5326 mL	12.6630 mL	25.3261 mL
5 mM	0.5065 mL	2.5326 mL	5.0652 mL
10 mM	0.2533 mL	1.2663 mL	2.5326 mL
50 mM	0.0507 mL	0.2533 mL	0.5065 mL

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