Description：

Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM in cell-free assays. Phase 2.

Chemical Information：

Molecular Weight (MW)		475.97
Formula		C24H27N3O4.HCl.H2O
CAS No.		732302-99-7
Solubility (25°C) *	DMSO	95 mg/mL (199.59 mM)
	Water	Insoluble
	Alcohol	3 mg/mL (6.3 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1010 mL	10.5049 mL	21.0097 mL
5 mM	0.4202 mL	2.1010 mL	4.2019 mL
10 mM	0.2101 mL	1.0505 mL	2.1010 mL
50 mM	0.0420 mL	0.2101 mL	0.4202 mL

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