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Description:
Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM in cell-free assays, respectively. Phase 2.
Chemical Information:
Molecular Weight (MW) 615.73 Formula
C32H41N9O4
CAS No. 1197160-78-3 Solubility (25°C) * DMSO 2 mg/mL (3.24 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.6241 mL 8.1204 mL 16.2409 mL 5 mM 0.3248 mL 1.6241 mL 3.2482 mL 10 mM 0.1624 mL 0.8120 mL 1.6241 mL 50 mM 0.0325 mL 0.1624 mL 0.3248 mL
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