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Description:
GDC-0879 is a novel, potent, and selective B-Raf inhibitor with IC50 of 0.13 nM in A375 and Colo205 cells with activity against c-Raf as well; no inhibition known to other protein kinases.
Chemical Information:
Molecular Weight (MW) 334.37 Formula
C19H18N4O2
CAS No. 905281-76-7 Solubility (25°C) * DMSO 66 mg/mL warmed (197.38 mM) Water Insoluble Alcohol 5 mg/mL (14.95 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.9907 mL 14.9535 mL 29.9070 mL 5 mM 0.5981 mL 2.9907 mL 5.9814 mL 10 mM 0.2991 mL 1.4953 mL 2.9907 mL 50 mM 0.0598 mL 0.2991 mL 0.5981 mL
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