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GDC-0623

GDC-0623

Catalog Number: CC7709 Rank: comment rank 5

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Description:

GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.

Chemical Information:

Molecular Weight (MW) 456.21
Formula

 

C16H14FIN4O3

 

CAS No. 1168091-68-6
Solubility (25°C) * DMSO 91 mg/mL warmed (199.46 mM)
Water Insoluble
Alcohol 5 mg/mL warmed (10.95 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.1920 mL 10.9599 mL 21.9197 mL
5 mM 0.4384 mL 2.1920 mL 4.3839 mL
10 mM 0.2192 mL 1.0960 mL 2.1920 mL
50 mM 0.0438 mL 0.2192 mL 0.4384 mL


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