Description：

GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with K_i of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.

Chemical Information：

Molecular Weight (MW)		452.55
Formula		C24H32N6O3
CAS No.		1207360-89-1
Solubility (25°C) *	DMSO	91 mg/mL (201.08 mM)
	Water	Insoluble
	Alcohol	6 mg/mL (13.25 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2097 mL	11.0485 mL	22.0970 mL
5 mM	0.4419 mL	2.2097 mL	4.4194 mL
10 mM	0.2210 mL	1.1049 mL	2.2097 mL
50 mM	0.0442 mL	0.2210 mL	0.4419 mL

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