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Description:
GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM in GLI1 expressing HEK293T cell, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.
Chemical Information:
Molecular Weight (MW) 429.6 Formula
C27H35N5
CAS No. 500579-04-4 Solubility (25°C) * DMSO Insoluble Water Insoluble Alcohol 12 mg/mL (27.93 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.3277 mL 11.6387 mL 23.2775 mL 5 mM 0.4655 mL 2.3277 mL 4.6555 mL 10 mM 0.2328 mL 1.1639 mL 2.3277 mL 50 mM 0.0466 mL 0.2328 mL 0.4655 mL
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