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Description:
Ganetespib (STA-9090) is an HSP90 inhibitor with IC50 of 4 nM in OSA 8 cells, induces apoptosis of OSA cells while normal osteoblasts are not affected; active metabolite of STA-1474. Phase 3.
Chemical Information:
Molecular Weight (MW) 364.4 Formula
C20H20N4O3
CAS No. 888216-25-9 Solubility (25°C) * DMSO 40 mg/mL (109.76 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.7442 mL 13.7212 mL 27.4424 mL 5 mM 0.5488 mL 2.7442 mL 5.4885 mL 10 mM 0.2744 mL 1.3721 mL 2.7442 mL 50 mM 0.0549 mL 0.2744 mL 0.5488 mL
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