Description：

Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.

Chemical Information：

Molecular Weight (MW)		469.94
Formula		C23H25ClFN7O
CAS No.		1229236-86-5
Solubility (25°C) *	DMSO	94 mg/mL (200.02 mM)
	Water	Insoluble
	Alcohol	9 mg/mL (19.15 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1279 mL	10.6397 mL	21.2793 mL
5 mM	0.4256 mL	2.1279 mL	4.2559 mL
10 mM	0.2128 mL	1.0640 mL	2.1279 mL
50 mM	0.0426 mL	0.2128 mL	0.4256 mL

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