Description：

AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.

Chemical Information：

Molecular Weight (MW)		414.56
Formula		C13H18Br2N2O.HCl
CAS No.		23828-92-4
Solubility (25°C) *	DMSO	4 mg/mL warmed (9.64 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

HSP90 62 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4122 mL	12.0610 mL	24.1220 mL
5 mM	0.4824 mL	2.4122 mL	4.8244 mL
10 mM	0.2412 mL	1.2061 mL	2.4122 mL
50 mM	0.0482 mL	0.2412 mL	0.4824 mL

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