Description：

Ambrisentan is a highly selective antagonist of the endothelin-1 type A receptor, used in the treatment of pulmonary arterial hypertension (PAH).

Chemical Information：

Molecular Weight (MW)		378.42
Formula		C22H22N2O4
CAS No.		177036-94-1
Solubility (25°C) *	DMSO	76 mg/mL (200.83 mM)
	Water	Insoluble
	Alcohol	22 mg/mL (58.13 mM)

Biological Activity：

Targets IC50

HSP90 5 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6426 mL	13.2128 mL	26.4257 mL
5 mM	0.5285 mL	2.6426 mL	5.2851 mL
10 mM	0.2643 mL	1.3213 mL	2.6426 mL
50 mM	0.0529 mL	0.2643 mL	0.5285 mL

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