Description：

FTI 277 HCl is the methyl ester of FTI 277, which is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I.

Chemical Information：

Molecular Weight (MW)		484.07
Formula		C22H30ClN3O3S2
CAS No.		180977-34-8
Solubility (25°C) *	DMSO	96 mg/mL (198.31 mM)
	Water	17 mg/mL (35.11 mM)
	Alcohol	14 mg/mL warmed (28.92 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0658 mL	10.3291 mL	20.6582 mL
5 mM	0.4132 mL	2.0658 mL	4.1316 mL
10 mM	0.2066 mL	1.0329 mL	2.0658 mL
50 mM	0.0413 mL	0.2066 mL	0.4132 mL

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