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Evacetrapib (LY2484595)

Evacetrapib (LY2484595)

Catalog Number: CC3081 Rank: comment rank 5

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Description:

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.

Chemical Information:

Molecular Weight (MW) 638.65
Formula

 

C31H36F6N6O2

 

CAS No. 1186486-62-3
Solubility (25°C) * DMSO 12.8 mg/mL (20.04 mM)
Water Insoluble
Alcohol 12.8 mg/mL (20.04 mM)


Biological Activity:

Targets
IC50
Tyrosinase
50 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.5658 mL 7.8290 mL 15.6580 mL
5 mM 0.3132 mL 1.5658 mL 3.1316 mL
10 mM 0.1566 mL 0.7829 mL 1.5658 mL
50 mM 0.0313 mL 0.1566 mL 0.3132 mL


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