Description：

Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM in cell-free assays, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.

Chemical Information：

Molecular Weight (MW)		429.90
Formula		C22H23N3O4.HCl
CAS No.		183319-69-9
Solubility (25°C) *	DMSO	4 mg/mL warmed (9.3 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

β2 receptor β1 recepto 32.6 nM 0.76 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3261 mL	11.6306 mL	23.2612 mL
5 mM	0.4652 mL	2.3261 mL	4.6522 mL
10 mM	0.2326 mL	1.1631 mL	2.3261 mL
50 mM	0.0465 mL	0.2326 mL	0.4652 mL

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