Description：

Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.

Chemical Information：

Molecular Weight (MW)		461.51
Formula		C18H21N5O2.C7H6O2
CAS No.		850649-62-6
Solubility (25°C) *	DMSO	68 mg/mL (147.34 mM)
	Water	2 mg/mL (4.33 mM)
	Alcohol	Insoluble

Biological Activity：

Targets IC50

c-Met Tie2 Ret VEGFR2 Flt-1/3/4 c-Kit 1.3 nM 14.3 nM 4 nM 0.035 nM 12 nM/11.3 nM/6 4.6 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1668 mL	10.8340 mL	21.6680 mL
5 mM	0.4334 mL	2.1668 mL	4.3336 mL
10 mM	0.2167 mL	1.0834 mL	2.1668 mL
50 mM	0.0433 mL	0.2167 mL	0.4334 mL

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